New publication on DECORIN, a triceps-derived myokine, and type 2 diabetes on Acta Physiol (Oxf)

"DECORIN, a triceps-derived myokine, protects sorted β-cells and human islets against chronic inflammation associated with type 2 diabetes"

Langlois A, Cherfan J, Meugnier E, Rida A, Arous C, Peronet C, Hamdard H, Zarrouki B, Wehrle-Haller B, Pinget M, Craige SM, Bouzakri K

A good news to start the year:  CeeD laboratory reveals a new publication in Acta Physiologica journal 

• In this paper, the research team shows that DECORIN, a new triceps-derived myokine, has a beneficial effect on human pancreatic islets, protecting them from cell death induced by inflammation.
• This work demonstrates for the first time that DECORIN restores T2D-islet function and reverses the expression of T2D-associated genes.
• Based on these datas, they propose DECORIN as a promising therapeutic target for diabetes-associated inflammation and diabetes itself.